Enable "Proxy through client access server" receive Error 530

I'm using Exchange 2013, I using Yahoo! mail and Gmail as smart host. If I enable the "Proxy through client access server" on my send connector, I will receive 530 authentication error.

smtp114.mail.ne1.yahoo.com Remote Server returned '530 authentication required

mx.google.com Remote Server returned '530-5.5.1 Authentication Required. Learn more at 530 5.5.1 

If I disable  "Proxy through client access server", the mail can be sent from mailbox role server. is there anythings wrong with my config?

Thanks.